ncRNA name | mmu-miR-155 |
ncRNA Category | miRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Mus musculus |
Tissues/Cell_line | bone marrow-derived macrophages (BMDM) |
Methods | Western blot, RT-PCR, ELISA, histologic analysis, fluorescein angiography |
Expression pattern | down-regulated |
Functional description | We conclude that C/EBPβ plays a significant role in M2 macrophage polarization in CNV model, while miR-155 mimics could suppress CNV by inhibiting C/EBPβ activity and M2 macrophage polarization. |
PubMed ID | 28965281 |
Year | 2018 |
Title | MicroRNA-155 Inhibits Polarization of Macrophages to M2-Type and Suppresses Choroidal Neovascularization. |
Drug-related ncRNA | NO |
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